http://endodoc.org/2008/04/11/how-do-you-tell-if-its-type-1-or-type-2-diabetes/ Potpourri of Pediatric Endocrinology Fri, 18 May 2012 01:52:26 +0000 hourly 1 http://wordpress.org/?v=3.3.2 http://endodoc.org/2008/04/11/how-do-you-tell-if-its-type-1-or-type-2-diabetes/comment-page-1/#comment-143560 endodoc Sun, 30 Oct 2011 10:48:19 +0000 http://endodoc.org/2008/04/11/how-do-you-tell-if-its-type-1-or-type-2-diabetes/#comment-143560 I have no idea what type 2.5 is. MODY (maturity-onset diabetes of youth) is a group of disorders characterized as type 2 diabetes-like conditions inherited in autosomal dominant fashion. The disorder is frequently diagnosed in childhood or adolescence. There are several genetic variants. There was a recent excellent review on the subject (Fajans SS, Bell GI: MODY. Diabetes Care 2011;34:1878-84). Type 1.5 is not really a specific disorder but a clinical diagnosis to describe patients in whom one cannot be certain if they have type 1 or type 2 diabetes. So-called LATA or latent autoimmune diabetes in adults is really just type 1 diabetes with clinical onset in adulthood. The best way to tell if a person has autoimmune type 1 diabetes is to measure various autoimmune markers such as GAD antibodies, islet-cell antibodies, etc. It's worth knowing if a patient has autoimmune type 1 or not since monitoring for autoimmune diseases is important (e.g., celiac disease, chronic lymphocytic thyroiditis, pernicious anemia). Sometimes it is not possible to classify a patient's type of diabetes but remember- treatment goals are the same for all types of diabetes. I have no idea what type 2.5 is. MODY (maturity-onset diabetes of youth) is a group of disorders characterized as type 2 diabetes-like conditions inherited in autosomal dominant fashion. The disorder is frequently diagnosed in childhood or adolescence. There are several genetic variants. There was a recent excellent review on the subject (Fajans SS, Bell GI: MODY. Diabetes Care 2011;34:1878-84). Type 1.5 is not really a specific disorder but a clinical diagnosis to describe patients in whom one cannot be certain if they have type 1 or type 2 diabetes. So-called LATA or latent autoimmune diabetes in adults is really just type 1 diabetes with clinical onset in adulthood. The best way to tell if a person has autoimmune type 1 diabetes is to measure various autoimmune markers such as GAD antibodies, islet-cell antibodies, etc. It’s worth knowing if a patient has autoimmune type 1 or not since monitoring for autoimmune diseases is important (e.g., celiac disease, chronic lymphocytic thyroiditis, pernicious anemia). Sometimes it is not possible to classify a patient’s type of diabetes but remember- treatment goals are the same for all types of diabetes.

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